D Xie Selected Research

Liver Neoplasms (Liver Cancer)

3/2014

Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.

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D Xie Research Topics

Disease

22	Neoplasms (Cancer) 01/2021 - 12/2000
8	Neoplasm Metastasis (Metastasis) 08/2021 - 02/2006
5	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 02/2006
5	Breast Neoplasms (Breast Cancer) 12/2020 - 03/2000
3	Carcinogenesis 01/2017 - 01/2006
3	Carcinoma (Carcinomatosis) 01/2017 - 12/2000
3	Colorectal Neoplasms (Colorectal Cancer) 11/2014 - 12/2000
2	Stomach Neoplasms (Stomach Cancer) 08/2021 - 10/2018
2	Lung Neoplasms (Lung Cancer) 04/2013 - 01/2010
2	Nonsyndromic Deafness 04/2012 - 06/2000
2	Hearing Loss (Hearing Impairment) 01/2012 - 06/2000
2	Deafness (Deaf Mutism) 01/2012 - 06/2000
2	Glioma (Gliomas) 04/2009 - 01/2006
2	Diabetes Mellitus 11/2006 - 11/2000
2	Diabetic Nephropathies (Diabetic Nephropathy) 11/2006 - 02/2006
2	Body Weight (Weight, Body) 11/2006 - 02/2006
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021
1	Starvation 09/2020
1	Acute Lung Injury 01/2020
1	Osteoarthritis 01/2017
1	Tuberous Sclerosis (Bourneville's Disease) 01/2017
1	Adenocarcinoma 01/2016
1	Brain Edema (Cerebral Edema) 01/2016
1	Central Nervous System Diseases (CNS Diseases) 01/2016
1	Edema (Dropsy) 01/2016
1	Urinary Bladder Neoplasms (Bladder Cancer) 02/2015
1	Ovarian Neoplasms (Ovarian Cancer) 01/2015
1	Cystadenoma 01/2015
1	Esophageal Squamous Cell Carcinoma 10/2014
1	Prostatic Neoplasms (Prostate Cancer) 04/2014
1	Liver Neoplasms (Liver Cancer) 03/2014

Drug/Important Bio-Agent (IBA)

5	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 03/2000
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2006
5	Messenger RNA (mRNA)IBA 11/2006 - 10/2001
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2000
3	Estrogen ReceptorsIBA 12/2020 - 04/2001
3	CreatinineIBA 05/2007 - 02/2006
2	EnzymesIBA 11/2017 - 01/2000
2	Biological ProductsIBA 01/2017 - 10/2014
2	Small Interfering RNA (siRNA)IBA 12/2016 - 02/2012
2	Pharmaceutical PreparationsIBA 01/2016 - 05/2015
2	LigandsIBA 02/2012 - 10/2001
2	Connexin 26IBA 01/2012 - 06/2000
2	AgarIBA 08/2009 - 04/2001
2	Transforming Growth Factor beta (TGF-beta)IBA 11/2006 - 02/2006
2	Streptozocin (Streptozotocin)FDA Link 11/2006 - 02/2006
2	Blood Glucose (Blood Sugar)IBA 11/2006 - 11/2000
2	Angiotensin IIIBA 11/2006 - 02/2006
2	Complementary DNA (cDNA)IBA 04/2001 - 06/2000
2	Estrogens (Estrogen)FDA Link 04/2001 - 02/2001
1	NF-kappa B (NF-kB)IBA 08/2021
1	5-hydroxymethylcytosineIBA 01/2021
1	Cell-Free Nucleic AcidsIBA 01/2021
1	Trastuzumab (Herceptin)FDA Link 12/2020
1	Progesterone Receptors (Progesterone Receptor)IBA 12/2020
1	APTIBA 12/2020
1	human ERBB2 proteinIBA 12/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 12/2020
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 09/2020
1	Phosphates (Orthophosphate)IBA 09/2020
1	Acid PhosphataseIBA 09/2020
1	glutaminyl- glutamyl- glutaminyl- leucyl- glutamyl- arginyl- alanyl- leucyl- asparagyl- seryl- serineIBA 01/2020
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 10/2018
1	Carcinoembryonic AntigenIBA 10/2018
1	NADP (NADPH)IBA 11/2017
1	Glutathione (Reduced Glutathione)IBA 11/2017
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2017
1	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 11/2017
1	Denosumab FDA Link 11/2017
1	Zoledronic Acid (Zometa)FDA Link 11/2017
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2017
1	Type 1 Parathyroid Hormone Receptor (Parathyroid Hormone Receptor)IBA 01/2017
1	ChloridesIBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017
1	K Cl- CotransportersIBA 01/2017
1	Matrix Metalloproteinases (MMPs)IBA 01/2017
1	Aquaporins (Water Channels)IBA 01/2016
1	Mannitol (Osmitrol)FDA LinkGeneric 01/2016
1	MelatoninIBA 01/2016
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2016
1	Sodium-Hydrogen ExchangersIBA 01/2016
1	Neuroprotective AgentsIBA 01/2016
1	Aquaporin 4IBA 01/2016
1	ras ProteinsIBA 05/2015
1	ProhibitinsIBA 02/2015
1	Histones (Histone)IBA 01/2015
1	Lysine (L-Lysine)FDA Link 01/2015
1	CateninsIBA 11/2014
1	LuciferasesIBA 09/2014
1	MicroRNAs (MicroRNA)IBA 04/2014
1	Androgen Receptors (Androgen Receptor)IBA 04/2014
1	Peptide Initiation Factors (Initiation Factor)IBA 04/2014
1	longikaurin AIBA 03/2014

Therapy/Procedure

4	Therapeutics 01/2016 - 11/2000
3	Drug Therapy (Chemotherapy) 12/2020 - 01/2012
1	Gastrectomy 10/2018
1	Chemoradiotherapy 10/2014
1	Radiotherapy 10/2014
1	Cystectomy 04/2014